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Title
Text copied to clipboard!Medicinal Chemist
Description
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We are looking for a highly skilled and motivated Medicinal Chemist to join our dynamic team. The ideal candidate will have a strong background in organic chemistry and a passion for drug discovery and development. As a Medicinal Chemist, you will be responsible for designing, synthesizing, and optimizing small molecules with the potential to become new therapeutic agents. You will work closely with biologists, pharmacologists, and other scientists to understand the biological targets and mechanisms of action, and to translate this knowledge into the design of effective and safe drugs. Your role will involve the use of state-of-the-art techniques and technologies in organic synthesis, analytical chemistry, and computational chemistry. You will also be expected to stay current with the latest scientific literature and advancements in the field, and to contribute to the scientific community through publications and presentations. The successful candidate will have excellent problem-solving skills, attention to detail, and the ability to work both independently and as part of a multidisciplinary team. This is an exciting opportunity to make a significant impact on the development of new medicines and to advance your career in a fast-paced and innovative environment.
Responsibilities
Text copied to clipboard!- Design and synthesize novel small molecules for drug discovery.
- Optimize lead compounds for potency, selectivity, and pharmacokinetic properties.
- Collaborate with biologists and pharmacologists to understand biological targets.
- Utilize computational chemistry tools to aid in drug design.
- Perform structure-activity relationship (SAR) studies.
- Develop and implement synthetic routes for complex molecules.
- Analyze and interpret experimental data.
- Maintain accurate and detailed laboratory records.
- Stay current with scientific literature and advancements in the field.
- Present research findings at internal and external meetings.
- Contribute to the preparation of scientific publications and patents.
- Ensure compliance with safety and regulatory guidelines.
- Mentor and train junior scientists and technicians.
- Participate in project planning and management.
- Collaborate with external partners and CROs.
- Manage laboratory resources and supplies.
- Troubleshoot and resolve technical issues.
- Contribute to the development of new research strategies.
- Support the preparation of grant applications and funding proposals.
- Engage in continuous professional development and training.
Requirements
Text copied to clipboard!- Ph.D. in Organic Chemistry, Medicinal Chemistry, or a related field.
- Strong background in synthetic organic chemistry.
- Experience in drug discovery and development.
- Proficiency in modern analytical techniques (NMR, MS, HPLC).
- Familiarity with computational chemistry tools.
- Excellent problem-solving and critical thinking skills.
- Strong attention to detail and organizational skills.
- Ability to work independently and as part of a team.
- Effective communication and presentation skills.
- Proven track record of scientific publications and/or patents.
- Knowledge of pharmacology and biology is a plus.
- Experience with structure-activity relationship (SAR) studies.
- Ability to manage multiple projects and deadlines.
- Strong commitment to laboratory safety and compliance.
- Experience with high-throughput screening and automation is a plus.
- Proficiency in data analysis and interpretation.
- Ability to mentor and train junior staff.
- Experience with project management and planning.
- Strong collaborative and interpersonal skills.
- Willingness to engage in continuous learning and development.
Potential interview questions
Text copied to clipboard!- Can you describe your experience with synthetic organic chemistry?
- How have you contributed to drug discovery projects in the past?
- What techniques do you use for optimizing lead compounds?
- How do you stay current with advancements in medicinal chemistry?
- Can you provide an example of a challenging problem you solved in the lab?
- How do you approach collaboration with biologists and pharmacologists?
- What computational chemistry tools are you familiar with?
- How do you ensure accuracy and detail in your laboratory records?
- Can you discuss a time when you had to troubleshoot a technical issue?
- How do you manage multiple projects and deadlines?
- What is your experience with structure-activity relationship (SAR) studies?
- How do you ensure compliance with safety and regulatory guidelines?
- Can you describe a successful project you led or contributed to?
- How do you mentor and train junior scientists?
- What strategies do you use for effective data analysis and interpretation?
- How do you handle setbacks or failures in your research?
- What is your experience with high-throughput screening and automation?
- How do you contribute to the preparation of scientific publications and patents?
- Can you discuss your experience with project management and planning?
- What motivates you to work in the field of medicinal chemistry?