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Title

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Medicinal Chemist

Description

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We are looking for a highly skilled and innovative Medicinal Chemist to join our pharmaceutical research and development team. The ideal candidate will have a strong background in organic chemistry, drug design, and molecular modeling, with a passion for discovering and optimizing new therapeutic compounds. As a Medicinal Chemist, you will play a critical role in the early stages of drug discovery, working closely with biologists, pharmacologists, and other chemists to design molecules that have the potential to become safe and effective medications. Your primary responsibilities will include designing and synthesizing novel chemical entities, analyzing structure-activity relationships (SAR), and optimizing lead compounds for potency, selectivity, and pharmacokinetic properties. You will also be expected to contribute to the development of synthetic routes, troubleshoot synthetic challenges, and maintain detailed records of your experimental work. Collaboration and communication are key, as you will be part of a multidisciplinary team working toward common goals in drug discovery and development. The successful candidate will have a Ph.D. in Medicinal Chemistry, Organic Chemistry, or a related field, along with experience in a pharmaceutical or biotech setting. Strong problem-solving skills, attention to detail, and the ability to manage multiple projects simultaneously are essential. Familiarity with modern analytical techniques, such as NMR, LC-MS, and HPLC, is required, as is proficiency in using cheminformatics and molecular modeling software. This is an exciting opportunity to contribute to the discovery of new medicines that can improve and save lives. If you are passionate about chemistry and want to make a meaningful impact in healthcare, we encourage you to apply.

Responsibilities

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  • Design and synthesize novel small molecules for drug discovery
  • Analyze structure-activity relationships (SAR) to optimize lead compounds
  • Develop and improve synthetic routes for target molecules
  • Collaborate with cross-functional teams including biology and pharmacology
  • Maintain accurate and detailed laboratory records
  • Interpret analytical data (NMR, LC-MS, HPLC) to confirm compound identity and purity
  • Contribute to project planning and decision-making processes
  • Present research findings to internal teams and stakeholders
  • Stay current with scientific literature and emerging technologies
  • Ensure compliance with safety and regulatory standards

Requirements

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  • Ph.D. in Medicinal Chemistry, Organic Chemistry, or related field
  • 3+ years of experience in pharmaceutical or biotech industry
  • Strong knowledge of synthetic organic chemistry
  • Experience with SAR analysis and lead optimization
  • Proficiency in analytical techniques such as NMR, LC-MS, and HPLC
  • Familiarity with molecular modeling and cheminformatics tools
  • Excellent problem-solving and critical thinking skills
  • Strong written and verbal communication abilities
  • Ability to work independently and in a team environment
  • Detail-oriented with strong organizational skills

Potential interview questions

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  • What experience do you have in medicinal or organic chemistry?
  • Can you describe a successful drug discovery project you contributed to?
  • How do you approach optimizing lead compounds?
  • What analytical techniques are you most proficient in?
  • How do you stay updated with the latest research in medicinal chemistry?
  • Describe a time you overcame a synthetic challenge in the lab.
  • What software tools do you use for molecular modeling?
  • How do you prioritize tasks when managing multiple projects?
  • What role do you typically play in cross-functional teams?
  • Why are you interested in this position?